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Kosmos
Astronomia Astrofizyka
Inne

Kultura
Sztuka dawna i współczesna, muzea i kolekcje

Metoda
Metodologia nauk, Matematyka, Filozofia, Miary i wagi, Pomiary

Materia
Substancje, reakcje, energia
Fizyka, chemia i inżynieria materiałowa

Człowiek
Antropologia kulturowa Socjologia Psychologia Zdrowie i medycyna

Wizje
Przewidywania Kosmologia Religie Ideologia Polityka

Ziemia
Geologia, geofizyka, geochemia, środowisko przyrodnicze

Życie
Biologia, biologia molekularna i genetyka

Cyberprzestrzeń
Technologia cyberprzestrzeni, cyberkultura, media i komunikacja

Działalność
Wiadomości | Gospodarka, biznes, zarządzanie, ekonomia

Technologie
Budownictwo, energetyka, transport, wytwarzanie, technologie informacyjne

Effects of Repetitive Transcranial Magnetic Stimulation on Dystonia: An Overview

Problem statement: Repetitive Transcranial Magnetic Stimulation (rTMS) is a noninvasive procedure whereby a pulsed magnetic field stimulates electrical activity in the brain. Dystonia is characterized by several disabling symptoms for which effective, mechanism-based treatments remain elusive. Approach: Consequently, more advanced non-invasive therapeutic methods were required. A possible method to modulate brain activity and potentially viable for use in clinical practice was rTMS. We focus on the basic foundation of rTMS, the effects of rTMS on neuroplasticity and sensorimotor integration and the experimental advances of rTMS that may become a viable clinical application to treat dystonia. Results: The findings showed that rTMS can improve some symptoms associated with dystonia and might be useful for promoting cortical plasticity in dystonic patients. These changes were transient and it is premature to propose these applications as realistic therapeutic options, even though the rTMS technique has shown itself to be, potentially, a modulator of sensorimotor integration and neuroplasticity. Conclusion/Recommendations: Functional imaging of the region of interest could highlight the capacity of rTMS to bring about plastic changes of the cortical circuitry and hint at future novel clinical interventions. We recommend further studies to clearly determine the role of rTMS in the treatment of these conditions. Finally, we must remember that however exciting the neurobiological mechanisms might be, the clinical usefulness of rTMS will be determined by their ability to provide patients with neurological and psychiatric disorders with safe, long-lasting and substantial improvements in quality of life.

American Journal of Neuroscience 2011/08/14 - 16:34 Czytaj